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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC37 All Species: 11.21
Human Site: T578 Identified Species: 24.67
UniProt: Q494V2 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q494V2 NP_872434.2 611 71117 T578 I K K K R G R T L V C R S R P
Chimpanzee Pan troglodytes XP_516716 600 69770 T567 I K K K R G R T L V C R S R P
Rhesus Macaque Macaca mulatta XP_001114297 608 70869 T575 I K K K R G R T L V C R S Q P
Dog Lupus familis XP_851379 703 79265 R670 I K R K R G R R L V C R S R P
Cat Felis silvestris
Mouse Mus musculus Q80VN0 459 53845 L427 K K K R G R K L I S R S H P P
Rat Rattus norvegicus XP_001076288 604 70773 K571 I K K K R G R K L L C R S H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509164 298 34913 L266 K K K T G R R L T Y R S E P H
Chicken Gallus gallus XP_425162 571 67562 R538 I E K K T G R R L M F R S S P
Frog Xenopus laevis Q6NRC9 1030 118723 T948 L Q C Q K V I T E K L R S V D
Zebra Danio Brachydanio rerio NP_001070228 547 64075 K514 V K K P S V K K L M P R S Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187699 537 62535 K504 P K K K T G R K L V Y R S E P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 91.9 57 N.A. 51.8 66.1 N.A. 27.9 41.4 20.7 38.6 N.A. N.A. N.A. N.A. 41
Protein Similarity: 100 97.5 95.2 66.4 N.A. 62 80.3 N.A. 37.4 61.5 35.5 58.4 N.A. N.A. N.A. N.A. 63.5
P-Site Identity: 100 100 93.3 86.6 N.A. 20 80 N.A. 20 60 20 40 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 100 100 93.3 N.A. 40 86.6 N.A. 20 73.3 46.6 66.6 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 46 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 10 0 0 0 0 0 0 10 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 19 64 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 10 % H
% Ile: 55 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % I
% Lys: 19 82 82 64 10 0 19 28 0 10 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 19 73 10 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 10 0 0 0 0 0 0 10 0 0 19 82 % P
% Gln: 0 10 0 10 0 0 0 0 0 0 0 0 0 19 0 % Q
% Arg: 0 0 10 10 46 19 73 19 0 0 19 82 0 28 0 % R
% Ser: 0 0 0 0 10 0 0 0 0 10 0 19 82 10 0 % S
% Thr: 0 0 0 10 19 0 0 37 10 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 19 0 0 0 46 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _